City profile · Cuba · North America
Santo Domingo
City population
45,476
#47
in Cuba
#5
in Villa Clara Province
#12,437
worldwide
22.587, -80.243 · 228 km from Havana
About Santo Domingo
Santo Domingo is a city in Villa Clara Province, Cuba with a population of 45,476. It is the 47th largest of the 123 cities of 15,000 or more listed in Cuba, and the 12,437th largest worldwide. It lies 228 km from Havana.
Key Facts
Country
Region
Rank in region
#5of 12
Coordinates
22.587, -80.243
Record updated
17 June 2026
Entry edited, not measured
City population, GeoNames. GeoNames publishes no year for its population figures, so “record updated” is when the entry was last edited — not the date the population was measured. Elevation is modelled from a digital elevation model rather than surveyed, so it is approximate.
Nearby Cities
All 123 in CubaClosest listed cities by great-circle distance from the city centre.